May 20, 2022

Overall Survival and Biomarker Analysis of Neoadjuvant Nivolumab Plus Chemotherapy in Operable Stage IIIA Non–Small-Cell Lung Cancer

Te group of Dr Atocha Romero has just published the terrific results of the NADIM phase II trial, showing that ctDNA levels were significantly associated with OS and outperformed radiologic assessments in the prediction of survival. The manuscript is available at https://ascopubs.org/doi/full/10.1200/JCO.21.02660#.YoK7H6Useqs.twitter

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May 4, 2022

Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis

A new piece of work from Dr Peinado´s group in which the medical oncologist Alberto Carretero, co-supervised with Guillermo De Velasco Oria de Rueda and Marta Herguetas characterize in depth circulating EVs from patients with brain metastasis. The manuscript is available at

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April 29, 2022

Commonly used methods for extracellular vesicles’ enrichment: Implications in downstream analyses and use

As part of the Special Issue on EVs at the European Journal of Cell Biology, Marta Clos-San Salvador and Marta Monguió-Tortajada from Dr Borrás´s group (REMAR-IVECAT Research Group (Kidney Related Pathologies Research Group – Innovation in Vesicles and Cells for Application in Therapy) at IGTP (Germans Trias i Pujol Health Sciences Research Institute)) nicely update […]

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March 30, 2022

ALK-Fusion Transcripts Can Be Detected in Extracellular Vesicles (EVs) from Nonsmall Cell Lung Cancer Cell Lines and Patient Plasma: Toward EV-Based Noninvasive Testing

A great work from the group of Dr Mariano Provencio and Dr Atocha Romero in collaboration with other TeNTaCLES members Dr Valés-Gómez and Dr Pardo. The manuscript is freely available to the scientific community at https://academic.oup.com/clinchem/advance-article/doi/10.1093/clinchem/hvac021/6554744#.YkH0kcWcq1s.whatsapp

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February 11, 2022

A simple immunoassay for extracellular vesicle liquid biopsy in microliters of non‑processed plasma

The latest publication from Dr Valés-Gómez group is now available in Journal of Nanobiotechnology. In this article they describe how to detect oncologic biomarkers in exosomes in just 12 microlitres of patients’ plasma. A high-throughput automatable method which allows the study of large cohorts of patients. The manuscript is freely available to the scientific community […]

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November 29, 2021

ExtracellularVesicles and engineered scaffolds to treat myocardial infarction

GIEVEX has hosted the ISEV #EVClub in which Dr Marta Monguió-Tortajada has presented their work on #ExtracellularVesicles and engineered scaffolds to treat myocardial infarction https://www.sciencedirect.com/…/pii/S2452199X21000840 You can find this interesting talk at https://www.youtube.com/watch?v=9M6xE6pLdds

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November 27, 2021

Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism

Dr Héctor Peinado publishes in Nature Cancer the relevance of tumoral EV in metastasis and lymphangiogenesis. Congrats to all authors of this terrific work. All details at: https://rdcu.be/cB2V6 https://www.elespanol.com/ciencia/salud/20211125/golpe-espanol-cancer-bloquean-metastasis-melanoma-laboratorio/629937407_0.html

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October 13, 2021

Jose Antonio López-Guerrero recibe el premio Prof Antonio Llombart Rodríguez y es nombrado Académico Correspondiente de la RAMCV

El PREMIO PROF. ANTONIO LLOMBART RODRÍGUEZ – FINCIVO 2020 y el nombramiento de Académico Correspondiente de la Real Academia de Medicina y Ciencias Afines de la Comunidad Valenciana, le ha correspondido al Dr. D. José Antonio López-Guerrero por su trabajo: “Predictive – Response Model to DNA-damaging agents based on genomic scars”. El PREMIO PROF. ANTONIO […]

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