July 12, 2021

Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis

Another piece of relevant information on the role of EVs in Melanoma metastasis. From Peinado´s group, of course. Congratulations! More details at: https://www.mdpi.com/1422-0067/22/14/7406

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July 5, 2021

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

Vesicle heterogeneity is a hot topic, and technology is starting to help us to unravel it. Learn more at this great review from Dr Falcón Perex group! https://www.nature.com/articles/s41596-021-00551-z?WT.mc_id=TWT_NatureProtocols&s=08

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June 29, 2021

Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles

A great revision on the different animal models focusing on nanoparticles and EVs from the Peinado´s group published on Advanced Drug Delivery Reviews- Congrats! https://www.sciencedirect.com/science/article/abs/pii/S0169409X21002258?dgcid=author

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June 18, 2021

Special Iss on EVs as non-coding RNA Delivery Systems in Inflammatory and Immunological Diseases

Dr. Raquel Cortes, Dr Javier Perez-Hernandez, Dr. Ana Ortega are organizing this Special Issue in Pharmaceutics (MDPI) and is open for submissions until 20th November 2021

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May 31, 2021

CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells

A TeNTaCLES collaboration between Yáñez-Mó and Peinado´s groups. Discover how: Tetraspanins are much more than EV markers Plasma membrane is an important source for EV cargo EV biogenesis impacts on mitochondrial quality control Biomedical potential of tetraspanin-targeted blocking peptides in tumor growth All the details at  http://doi.org/10.1002/jev2.12082

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March 17, 2021

Local administration of MSC-EVs in a myocardial infarction model

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction A collaboration between the iCREC and the IVECAT-REMAR groups from the Institute Germans Trias i Pujol (IGTP) has brought some new light into the therapeutic potential of MSC derived EVs. Check all the details in the link below. […]

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January 22, 2021

DNA-Loaded Extracellular Vesicles in Liquid Biopsy: Tiny Players With Big Potential?

Extracellular vesicles, tiny players with big potential ?, some ideas published by Susana Garcia Silva, Miguel Gallardo and Hector Peinado https://www.frontiersin.org/articles/10.3389/fcell.2020.622579/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field&journalName=Frontiers_in_Cell_and_Developmental_Biology&id=622579%E2%80%AC&fbclid=IwAR3ZlWgLIcdyjrsOEPMDZjQXiCrfBh8wtM0ptCRayh6D4Vm7ivjEtIYbBuc

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January 18, 2021


The group of Dr Pardo have have published a ground-breaking study of EVs on Obesity and its comorbidities. They isolated and characterized extracellular vesicles (EVs) shed by whole human obese visceral (VAT) and subcutaneous (SAT) adipose tissues to perform the first proteome reference map and comparative analysis. Further validation shows that obese AT release EVs […]

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December 18, 2020

Proteomic Characterization of urinary EVs from kidney Transplanted patients treated with CNIs

REMAR group led by Dr Francesc Borràs has recently published their study on proteomic profiling of urinary EVs. You read the full article at https://www.mdpi.com/1422-0067/21/20/7569

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