Extracellular vesicles, tiny players with big potential ?, some ideas published by Susana Garcia Silva, Miguel Gallardo and Hector Peinado https://www.frontiersin.org/articles/10.3389/fcell.2020.622579/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field&journalName=Frontiers_in_Cell_and_Developmental_Biology&id=622579%E2%80%AC&fbclid=IwAR3ZlWgLIcdyjrsOEPMDZjQXiCrfBh8wtM0ptCRayh6D4Vm7ivjEtIYbBuc
Read MoreThe group of Dr Pardo have have published a ground-breaking study of EVs on Obesity and its comorbidities. They isolated and characterized extracellular vesicles (EVs) shed by whole human obese visceral (VAT) and subcutaneous (SAT) adipose tissues to perform the first proteome reference map and comparative analysis. Further validation shows that obese AT release EVs […]
Read MoreREMAR group led by Dr Francesc Borràs has recently published their study on proteomic profiling of urinary EVs. You read the full article at https://www.mdpi.com/1422-0067/21/20/7569
Read MoreAn excellent review from Dr Peinado´s group in which they summarize the most recent findings in ovarian cancer metastasis, with special focus on the role of secreted factors and extracellular vesicles in ovarian cancer metastasis https://www.sciencedirect.com/science/article/pii/S1359634919300023
Read MoreAn excellent review from Dr Pardo´s group in which they describe the most frequent proteins identified in EVs shed by adipose tissue and its components, including their changes under pathological status, to give the reader a whole picture about the membrane/antigens, and intracellular proteins known so far, in an attempt to elucidate functional roles, and […]
Read MoreDr Yáñez-Mó has participated in a recent Editorial that was launched after the coming after last year´s fruitful discussion in Philadelphia in the ISEV Workshop devoted to “Extracellular Vesicle Targetting to cells and Tissues”. https://onlinelibrary.wiley.com/doi/full/10.1002/jev2.12032
Read MoreThe utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in Clinical Theranostic”, in which both Dr Marcilla and Dr Falcón-Perez participated. You can read in the recently published report, the interesting conclusions of […]
Read MoreMoving forward in the use of EVs as disease biomarkers, this seminal work published in Cell by the group of Dr Lyden with the contribution of Dr Hector Peinado. Original article can be found here: https://www.cell.com/cell/fulltext/S0092-8674(20)30874-6
Read MoreWhen Lydia Alvarez-Erviti started her postdoctoral studies at the University of Oxford, UK, in 2008, her goal was to develop gene therapies for neurodegenerative diseases. She had identified her target — α-synuclein, a protein that accumulates in the brains of people with Parkinson’s disease — and designed a short interfering RNA (siRNA) to reduce the […]
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