July 12, 2021

Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis

Another piece of relevant information on the role of EVs in Melanoma metastasis. From Peinado´s group, of course. Congratulations! More details at: https://www.mdpi.com/1422-0067/22/14/7406

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July 5, 2021

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

Vesicle heterogeneity is a hot topic, and technology is starting to help us to unravel it. Learn more at this great review from Dr Falcón Perex group! https://www.nature.com/articles/s41596-021-00551-z?WT.mc_id=TWT_NatureProtocols&s=08

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June 29, 2021

Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles

A great revision on the different animal models focusing on nanoparticles and EVs from the Peinado´s group published on Advanced Drug Delivery Reviews- Congrats! https://www.sciencedirect.com/science/article/abs/pii/S0169409X21002258?dgcid=author

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June 18, 2021

Special Iss on EVs as non-coding RNA Delivery Systems in Inflammatory and Immunological Diseases

Dr. Raquel Cortes, Dr Javier Perez-Hernandez, Dr. Ana Ortega are organizing this Special Issue in Pharmaceutics (MDPI) and is open for submissions until 20th November 2021

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May 31, 2021

CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells

A TeNTaCLES collaboration between Yáñez-Mó and Peinado´s groups. Discover how: Tetraspanins are much more than EV markers Plasma membrane is an important source for EV cargo EV biogenesis impacts on mitochondrial quality control Biomedical potential of tetraspanin-targeted blocking peptides in tumor growth All the details at  http://doi.org/10.1002/jev2.12082

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