April 16, 2021

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates

Alzheimer’s disease (AD), the most prevalent form of dementia, remains incurable mainly due to our failings in the search for effective pharmacological strategies. Here, we describe the development of targeted multimodal polypeptide-based nanoconjugates as potential AD treatments. Treatment with polypeptide nanoconjugates bearing propargylamine moieties and bisdemethoxycurcumin or genistein afforded neuroprotection and displayed neurotrophic effects, as […]

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March 24, 2021

Biomaterial scaffolds containing extracellular vesicles from stem cells to control and promote heart muscle repair after heart attack

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction A collaboration between the iCREC and the IVECAT-REMAR groups from the Institute Germans Trias i Pujol (IGTP) has brought some new light into the therapeutic potential of MSC derived EVs. Check all the details in the link below. […]

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January 22, 2021

DNA-Loaded Extracellular Vesicles in Liquid Biopsy: Tiny Players With Big Potential?

Extracellular vesicles, tiny players with big potential ?, some ideas published by Susana Garcia Silva, Miguel Gallardo and Hector Peinado https://www.frontiersin.org/articles/10.3389/fcell.2020.622579/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field&journalName=Frontiers_in_Cell_and_Developmental_Biology&id=622579%E2%80%AC&fbclid=IwAR3ZlWgLIcdyjrsOEPMDZjQXiCrfBh8wtM0ptCRayh6D4Vm7ivjEtIYbBuc

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January 20, 2021

Dr Marcilla elected as corresponding academic of the Spanish Royal Academy of Pharmacy

We are happy to announce that Dr Marcilla has been recently elected as corresponding academic at the Spanish Royal Academy of Pharmacy. Our TeNTaCLES network now counts with two academics (Dr Sánchez-Madrid and Dr Marcilla)! We will be looking forward to his position taking act to celebrate it!. Congrats!

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January 18, 2021

HUMAN OBESE WHITE ADIPOSE TISSUE SHEDS DEPOT-SPECIFIC EXTRACELLULAR VESICLES AND REVEALS CANDIDATE BIOMARKERS FOR MONITORING OBESITY AND ITS COMORBIDITIES

The group of Dr Pardo have have published a ground-breaking study of EVs on Obesity and its comorbidities. They isolated and characterized extracellular vesicles (EVs) shed by whole human obese visceral (VAT) and subcutaneous (SAT) adipose tissues to perform the first proteome reference map and comparative analysis. Further validation shows that obese AT release EVs […]

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January 14, 2021

Presence of GEIVEX and TeNTaCLES at ISEV and JEV.

GEIVEX VicePresident and member of the TeNTaCLES network Dr Falcón- Pérez is also forming part of the ISEV Board of Directors. And now two members of TeNTaCLES are in the Editorial Board of The Journal of Extracellular Vesicles: Dr Marcilla and Dr Peinado

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January 1, 2021

CURSO AVANZADO EN VESÍCULAS EXTRACELULARES

Se ha ampliado el plazo de matrícula! la fecha límite para la matrícula en la segunda edición del Curso Avanzado GEIVEX-UFV en Vesículas Extracelulares en español se ha retrasado al 15 de febrero. El programa incluya: Conceptos Básicos de la Biología y biogénesis de Vesículas Extracelulares. Dra. María Yáñez Mo. Centro de Biología Molecular Severo […]

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December 18, 2020

Proteomic Characterization of urinary EVs from kidney Transplanted patients treated with CNIs

REMAR group led by Dr Francesc Borràs has recently published their study on proteomic profiling of urinary EVs. You read the full article at https://www.mdpi.com/1422-0067/21/20/7569

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