September 2, 2022

N-Glycans in Immortalized Mesenchymal Stromal Cell-Derived Extracellular Vesicles Are Critical for EV–Cell Interaction and Functional Activation of Endothelial Cells

A collaborative work from Dr Borrás´s and Dr Falcón-Perez groups demonstrating the functional relevance of N-Glycans on the surface of EVs. The manuscript is available at https://www.mdpi.com/1422-0067/23/17/9539

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July 13, 2022

El Biobanco del Fundación Instituto Valenciano de Oncología (IVO), el primero en España en obtener la Acreditación internacional ISO20387

El biobanco de la Fundación Instituto Valenciano de Oncología (IVO), ha sido el primero en España en obtener la acreditación internacional ISO20387: una norma que avala la gestión de la calidad del material biológico, de las muestras de control y los datos obtenidos para la investigación biomédica. Para el jefe de servicio del laboratorio de […]

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June 14, 2022

Bioimplants with extra-cellular vesicles from stem cells can improve cardiac function after an acute myocardial heart attack

Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration in cardiovascular diseases) at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack in collaboration with the IVECAT group (IGTP). In an article published in Theranostics, they present a study of extracellular vesicles […]

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May 4, 2022

Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis

A new piece of work from Dr Peinado´s group in which the medical oncologist Alberto Carretero, co-supervised with Guillermo De Velasco Oria de Rueda and Marta Herguetas characterize in depth circulating EVs from patients with brain metastasis. The manuscript is available at

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May 3, 2022

Tetraspanins interweave EV secretion, endosomal network dynamics and cellular metabolism

As part of a Special Issue on EVs on the European J Cell Biology, Víctor Toribio and María Yáñez-Mó discuss how tetraspanins regulate endosomal dynamics and thus impact on EV secretion and cellular metabolism revieweing intriguing new data on this interesting superfamily of proteins. The manuscript is freely available to the scientific community at

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April 28, 2022

Commonly used methods for extracellular vesicles’ enrichment: Implications in downstream analyses and use

As part of a Special Issue on EVs on the European J Cell Biology, a nice update from Dr Borrás group on EV enrichment techniques that will help in decision making for downstream analyses. The manuscript is freely available to the scientific community at

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April 25, 2022

The Contribution of Extracellular Vesicles From Senescent Endothelial and Vascular Smooth Muscle Cells to Vascular Calcification

A mini-review article from GEIVEX members Dr Consuelo Borrás and Dr Matilde Alique. Vascular calcification is an irreversible pathological process associated with a loss of vascular wall function. This process occurs as a result of aging and age-related diseases, such as cardiovascular and chronic kidney diseases, and leads to comorbidities. During these age-related diseases, the […]

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